This test examines 710 genes linked to over 700 conditions that can cause miscarriage or problems with pregnancy development. These disorders are often the cause of repeated miscarriages.

1️⃣ Recurrent Pregnancy Loss (RPL)

Some women have genetic mutations affecting blood clotting or hormone regulation, leading to multiple miscarriages.
Genes involved: F2 (Prothrombin), F5 (Factor V Leiden), MTHFR (linked to folate metabolism).

2️⃣ Preeclampsia & Hypertension Disorders

Certain genetic variations make women more prone to high blood pressure, swelling, and organ damage during pregnancy.
Genes involved: FLT1, ENG, ACE (linked to vascular function).

3️⃣ Gestational Diabetes Mellitus (GDM)

Some women have genetic risk factors that increase insulin resistance during pregnancy.
Genes involved: TCF7L2, MTNR1B (related to glucose regulation).

4️⃣ Thrombophilia (Blood Clotting Disorders)

Genetic mutations can increase the risk of dangerous blood clots, which may cause miscarriage or pregnancy complications.
Genes involved: F5 (Factor V Leiden), F2 (Prothrombin mutation), MTHFR.

5️⃣ HELLP Syndrome (Hemolysis, Elevated Liver Enzymes, Low Platelets)

A severe pregnancy complication linked to inherited clotting disorders or immune dysfunction.
Genes involved: ACE, SERPINE1 (affecting blood pressure & clotting).

6️⃣ Intrauterine Growth Restriction (IUGR)

Genetic factors can impair placental function, leading to poor fetal growth.
Genes involved: NOS3, VEGFA (affecting blood flow to the placenta).

7️⃣ Eclampsia & Seizures During Pregnancy

Some genetic mutations increase the risk of severe high blood pressure leading to seizures.
Genes involved: AGT, REN (related to blood pressure regulation).

8️⃣ Cholestasis of Pregnancy (ICP)

A liver disorder where genetic mutations affect bile acid transport, leading to severe itching and risk of stillbirth.
Genes involved: ABCB11, ATP8B1 (bile acid transporters).

Early Detection – Allows preventive care and better pregnancy management.
Personalized Treatment – Doctors can tailor medications, diet, and monitoring based on the genetic risk.
Better Pregnancy Outcomes – Reduces risk of miscarriage, preterm birth, or complications.

There are many genetic disorders that can be checked before birth, but not all of them are tested for regularly

The test is performed at a U.S. CLIA-certified and CAP-accredited laboratory.
English clinical report will be issued by a U.S. board-certified medical director.

If you’ve had issues like miscarriages or problems with pregnancy development in the past, you may consider this test to determine the cause

If your doctor thinks you might be at risk for miscarriage or pregnancy issues, these tests can help you understand your risks better

We provide free referrals to physicians with substantial clinical genetic experience for pre- and post-test consultation.

Miscarriage English