OneOme RightMed Test
Pharmacogenomic (PGx) testing identifies how your genes affect your response to medications. Getting a PGx test may help your physician adjust your medications to be more effective for you.
When you take a medication, your body’s response is determined by many factors, including your gender, weight, age, diet, other medications, any medical conditions, and exposure to environmental agents such as cigarette smoke.
Your genetic makeup can also have a major influence. In fact, genetic factors can account for up to 95% of how you respond to medications. Genes are sections of DNA, and variations in your DNA are what make you unique. The different versions of a gene you inherit from your mother and father can determine everything from your eye color to how quickly you process, or metabolize medications.
Depending on your genes, your body may break down a drug too slowly or too quickly. If you metabolize a drug too slowly, you may be exposed to too much of it, which may result in an adverse drug reaction (ADR). If you metabolize a drug too quickly, you may not get enough to have any effect at all.
Rainbow Genomics works closely with OneOme (Minneapolis, MN, U.S,) to provide comprehensive, clinically- actionable pharmacogenomic test to patients and physicians - The OneOme® RightMed® pharmacogenomic test. The OneOme® solution was co-developed and exclusively licensed from Mayo Clinic to bring pharmacogenomics into routine clinical care. The OneOme RightMed pharmacogenomic test is currently in use by Mayo Clinic Center for Individualized Medicine and many other hospitals and clinics around the world.
OneOme® RightMed® test
Genetic factors can account for up to 95% of drug-response variability and susceptibility (1). In other words, how a drug will—or won't—work for a particular individual.
Recent studies have demonstrated that > 90% of patients possess clinically actionable genetic variants that affect their drug response (2, 3). The RightMed test can identify which inherited genetic variations a patient has to predict drug efficacy and metabolism and provide you with personalized recommendations for each of your patients.
The OneOme® RightMed® pharmacogenomic test is a cost-effective solution that determines how an individual patient’s genes may affect his/her response to medications. OneOme analyzes a patient’s genetic information and provides a validated clinical test report to help physicians and patients to make more precise and effective prescription decisions.
The RightMed test covers 22 genes, more than 350 medications, and 28 conditions.
During the office visit, your physician will also collect your DNA sample through a simple cheek swab for the OneOme RightMed® pharmacogenomic test. The sample will be sent to OneOme's CAP-accredited and CLIA-certified clinical testing laboratory. The OneOme clinical team will perform the testing, analysis and issue a clinical test report.
Is This Test Right For You?
Everyone can benefit from the OneOme RightMed test. Your test results can be used over the course of your lifetime to help you make better prescription decisions for many different medical conditions. While the RightMed test can provide insight for anyone, it’s particularly meaningful for patients who are taking:
MEDICATIONS THAT CAUSE UNWELCOME SIDE EFFECTS
MEDICATIONS THAT ARE NOT WORKING
MEDICATIONS FOR ANY OF THE COVERED MEDICAL CONDITIONS
For Physicians and Pharmacists
Preemptive Pharmacogenomic Testing for Precision Medicine: A Comprehensive Analysis of Five Actionable Pharmacogenomic Genes Using Next-Generation DNA Sequencing and a Customized CYP2D6 Genotyping Cascade. Yuan, J. et. al., Jmol Diag. 2016; 18(3): 438-445.